Owner Ortho-McNeil Pharmaceutical, Inc.

Inventors Meduna, Steven P.; Grice, Cheryl A.; Khatuya, Haripada; Wei, Jianmei; Cai, Hui; Tays, Kevin L.; Gustin, Darin J.; Pio, Barbara A.; Butler, Christopher R.; Edwards, James P.; Sehon, Clark A.

Agent Shelston IP

Pub. Number AU-B-2001286454

PCT Pub. Number WO02/14315

Priority 60225178 14.08.00 US; 09927324 10.08.01 US

Filing date 10 August 2001

Wipo publication date 25 February 2002

Acceptance publication date 14 September 2006

C07D 471/00 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

A61K 31/275 (2006.01) - Nitriles

A61K 31/4155 (2006.01) - not condensed and containing further heterocyclic rings

A61K 31/454 (2006.01)

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/14 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or