Owner Banyu Pharmaceutical Co., Ltd.

Inventors Numazawa, Tomoshige; Matsuda, Kenji; Kurihara, Hideki; Ogino, Yoshio; Noguchi, Kazuhito; Otake, Norikazu

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2001271027

PCT Pub. Number WO02/04402

Priority 2000-210591 11.07.00 JP

Filing date 10 July 2001

Wipo publication date 21 January 2002

Acceptance publication date 7 July 2005

C07C 219/10 Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton

A61K 031/55 - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61K 031/397 - having four-membered rings, e.g. azetidine

A61K 031/4525

A61P 027/16 Drugs for disorders of the senses

A61P 043/00 Drugs for specific purposes, not provided for in groups

A61P 011/06 Drugs for disorders of the respiratory system

A61P 011/00 Drugs for disorders of the respiratory system

A61K 031/407 - condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine

A61K 031/438 - the ring being spiro-condensed with carbocyclic or heterocyclic ring systems

A61K 031/5386

A61K 031/40 - having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil

A61K 031/395 - having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins

A61K 031/222

A61K 031/403 - condensed with carbocyclic rings, e.g. carbazole

A61K 031/4409 - only substituted in position 4, e.g. isoniazid, iproniazid

A61K 031/435 - having six-membered rings with one nitrogen as the only ring hetero atom

A61K 031/439 - the ring forming part of a bridged ring system, e.g. quinuclidine

A61K 031/452 - Piperidinium derivatives

C07D 239/06 Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 205/04 Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D 295/125 Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 211/70 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 211/22 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 487/10 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 471/10 Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 498/10 Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 209/52 Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 221/24 Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups

C07D 207/08 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 207/12 Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 451/02 Heterocyclic compounds containing condensed hetero ring systems

C07D 405/12 Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 211/46 Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07C 251/18 Compounds containing nitrogen atoms doubly- bound to a carbon skeleton

C07C 251/08 Compounds containing nitrogen atoms doubly- bound to a carbon skeleton

C07C 219/24 Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton

C07C 219/22 Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton