Pegylation of linkers improves antitumor activity and reduces toxicity of immunoconjugates

Details for Australian Patent Application No. 2001269762 (hide)

Owner The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services

Inventors Lee, Byungkook; Nagata, Satoshi; Onda, Masanori; Tsutsumi, Yasuo; Pastan, Ira H.

Agent Davies Collison Cave

Pub. Number AU-B-2001269762

PCT Pub. Number WO01/95942

Priority 60213804 22.06.00 US; 60211331 09.06.00 US

Filing date 8 June 2001

Wipo publication date 24 December 2001

Acceptance publication date 23 June 2005

International Classifications

A61K 047/48 Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates

Event Publications

23 June 2005 Assignment before Grant

  The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services; Kreitman, Robert J The application has been assigned to The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services

23 June 2005 Application Accepted

  Published as AU-B-2001269762

4 August 2005 Application for Amendment

  The nature of the amendment is as shown in the statement(s) filed 08 Jul 2005. Address for service in Australia - Davies Collison Cave Level 10 10 Barrack Street Sydney NSW 2000

20 October 2005 Standard Patent Sealed

22 December 2005 Amendment Made

  The nature of the amendment is as shown in the statement(s) filed 08 Jul 2005 2002

13 January 2011 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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