Owner Amgen Inc.

Inventors Egrie, Joan C.; Sitney, Karen C.; Browne, Jeffrey K; Elliott, Steven G

Agent Wrays

Pub. Number AU-B-2001255516

PCT Pub. Number WO01/81405

Priority 09559001 21.04.00 US

Filing date 19 April 2001

Wipo publication date 7 November 2001

Acceptance publication date 18 January 2007

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 38/22 (2006.01) Medicinal preparations containing peptides - Hormones

A61K 47/10 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Alcohols

A61K 47/12 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Carboxylic acids

A61K 47/42 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Proteins

A61P 7/06 (2006.01) Drugs for disorders of the blood or the extracellular fluid

C07K 14/505 (2006.01) Peptides having more than 20 amino acids

C07K 19/00 (2006.01) Hybrid peptides

C12N 1/15 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 1/19 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

A61K 38/00 (2006.01) Medicinal preparations containing peptides