Owner Amgen Inc.

Inventors Powers, Scott; Mu, David

Agent Spruson & Ferguson

Pub. Number AU-B-2001250794

PCT Pub. Number WO01/66741

Priority 60/186,915 03.03.00 US

Filing date 2 March 2001

Wipo publication date 17 September 2001

Acceptance publication date 2 March 2006

C12N 15/12 (2006.01) Mutation or genetic engineering - Genes encoding animal proteins

A61K 31/7088 (2006.01) - Compounds having three or more nucleosides or nucleotides

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61P 35/00 (2006.01) Antineoplastic agents

C07K 14/705 (2006.01) Peptides having more than 20 amino acids

C07K 16/28 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 1/21 (2006.01) Micro-organisms, e.g. protozoa - modified by introduction of foreign genetic material

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

C12N 15/63 (2006.01) Mutation or genetic engineering - Introduction of foreign genetic material using vectors

C12Q 1/68 (2006.01) Measuring or testing processes involving enzymes or micro-organisms - involving nucleic acids

G01N 33/53 (2006.01) Investigating or analysing materials by specific methods not covered by groups - Immunoassay

G01N 33/68 (2006.01) Investigating or analysing materials by specific methods not covered by groups - involving proteins, peptides or amino acids