Design and discovery of protein based TNF-alpha variants for the treatment of TNF-alpha related disorders

Details for Australian Patent Application No. 2001245411 (hide)

Owner Xencor

Inventors Filikov, Anton; Dahiyat, Bassil I.

Agent Freehills

Pub. Number AU-B-2001245411

PCT Pub. Number WO01/64889

Priority 60186427 02.03.00 US

Filing date 2 March 2001

Wipo publication date 12 September 2001

Acceptance publication date 1 September 2005

International Classifications

C12N 015/28 Mutation or genetic engineering

A61P 029/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61K 038/19 Medicinal preparations containing peptides - Cytokines

C07K 014/525 Peptides having more than 20 amino acids

Event Publications

1 September 2005 Application Accepted

  Published as AU-B-2001245411

5 January 2006 Standard Patent Sealed

25 September 2008 Application Lapsed, Refused Or Withdrawn, Patent Ceased or Expired

  This patent ceased under section 143(a), or Expired. Note that applications or patents shown as lapsed or ceased may be restored at a later date.

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